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Complementary preclinical studies in animal models demonstrate that GLP-1 RAs reduce alcohol craving and alcohol consumption, suggesting potential therapeutic benefit in alcohol use disorder (AUD)

Int J Sports Physiol Perform 6(1):2537 ter Steege RW, Kolkman JJ (2012) Review article: the pathophysiology and management of gastrointestinal symptoms during physical exercise, and the role of splanchnic blood flow

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This mechanism is also the source of cancer-related concerns (more below)