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In addition, treatment with enzalutamide (ENZ) and ARV-110, two anti-AR drugs, enhance the sensitivity of AR+ prostate cancer cells to ferroptosis by decreasing the expression of MBOAT2 [91]
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October 20, 2017
Meanwhile, following post-translational modifications in the cell, PCSK9 binds to the extracellular domain of LDLR, forming a PCSK9-LDLR complex, which is internalized via clathrin-coated pits and finally directed to lysosomes for degradation [48]
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