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These induce significant cell growth inhibition (63%) in MCF7 cells, and the expression of p21, caspase-9, and pro-apoptotic caspase-3, genes was increased in MCF7 cells treated with AEL, compared to those treated with control

This observation could indicate a potential role of GHK-Cu in limiting the activation or mobilization of neutrophils, possibly curtailing the oxidative bursts and consequent inflammation

Effect of chronic oxidative stress on neuroinflammatory response mediated by CD4+T cells in neurodegenerative diseases

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To further validate these findings, we replaced the AH of MmSNX1 with that of AtSNX1 and evaluated its membrane remodeling ability