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The NHS schedule for treating B12 deficiency is a loading dose of 1mg hydroxocobalamin by intramuscular injection every two to three days for two weeks, then a maintenance dose every two to three months for life when the cause is non-dietary

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Oxidative stress occupies a key position in the pathogenesis of PCOS, exacerbating ovarian dysfunction by promoting cell damage and apoptosis [26, 27]

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