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1 When diabetic patients are not at risk of DKA, basal insulin plus noninsulin hypoglycemic agents with weight loss effects are recommended for those with preobesity/obesity or without weight loss, and basal insulin/premix insulin plus secretagogues or DPP-4i are recommended for those without preobesity/obesity and with weight loss concerns

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In addition, APAP cases that did not develop liver injury, as well as patients who are receiving APAP at therapeutic doses are important controls that should be included in future clinical studies

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known as incretins that affect digestion, blood sugar level and appetite