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Increased Energy Expenditure Thanks to glucagon receptor activation, Retatrutide may burn more calories at rest and preferentially target stored body fat through hepatic lipolysis

RI = Referentie-Inname van een gemiddelde volwassene (8400 kJ / 2000 kcal)

It helps support antioxidant recycling, detoxification pathways, immune function, mitochondrial health, and cellular repair

Quick Summary Retatrutide is a triple agonist (GLP-1 + GIP + Glucagon), while Tirzepatide is dual (GLP-1 + GIP)

Increased release of glutamate from presynaptic terminals activates N -methyl-D-aspartate (NMDA) receptors on postsynaptic terminals to lead to a widespread neuronal depolarization or spreading depression, further disrupting the sodium ion, potassium ion, and calcium ion equilibria (Langlois et al., 2006)