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Last year, the MHRA said GPs should consider periodic vitamin B12 testing of higher-risk patients who take metformin, even if they dont display symptoms of deficiency The guidance warns not to rule out a diagnosis of vitamin B12 deficiency based solely on the absence of anaemia or macrocytosis

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Ohkawa H, Ohishi N, Yagi K

I think a lot of physicians, as well as the public, would make recommendations to patients to just eat better and do some exercise, and that is really an unhelpful prescription for patients with obesity, Harris said