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Therapeutic strategies targeting mitochondrial dysfunction for comorbidity intervention (Table 2) Enhancing mitochondrial energy metabolism Mitochondrial protectants Coenzyme Q10, a well-established clinical therapeutic agent, is a component of the ETC and plays a dual role in facilitating electron transfer and exerting potent antioxidant effects

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Moreover, a strong effect of the fasting intervention was observed in relation to amylase concentration decrease, indicating a significant reduction in carbohydrate stores in the men tested under these conditions

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