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While a modestly reduced risk for 14 obesity-related cancers was evident with GLP-1 drugs, the suggestion of a protective effect was particularly strong for colorectal malignancies

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doi: 10.1038/s41467-022-29018-9 61 HouWXieYSongXSunXLotzeMTZehHJet al

Obesity increased mitochondrial superoxide production (measured by MitoSOX staining) and increased cellular oxidative stress (measured by DHE staining) in the atria (Figures 4AD)