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In the 2025 study mentioned earlier, women receiving the combination therapy experienced an average weight loss of 6.09 kg (about 13.4 lbs) over 16 weeks, compared to 2.25 kg (approximately 5.0 lbs) in the metformin-only group

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A 12-week Pilates training significantly decreased gait and balance scale scores, foot reaction time, and PD Unified Rating Scale motor scores, while increasing step frequency, Berg Balance Scale scores, and functional reach-forward distances, and reducing time required for the stand-up-and-walk timed test in PD patients