Diagnosis is made by the finding of a diffuse, smooth, firm goiter in a young woman, with strongly positive titers of TG Ab and/or TPO Ab and a euthyroid or hypothyroid metabolic status
doi: 10.1258/0004563054889954
Since its release in 2017, the wonder drug has garnered overwhelming demand as we know, less for treating diabetes than for its weight loss effects
Novo Nordisks semaglutide, the GLP-1 analog used in Ozempic and Wegovy, showed an average weight loss of 10.6% at 68 weeks with the 2.4 mg dose in adults with type 2 diabetes and obesity or overweight in the STEP 2 Phase 3 trial
Conducting rigorous studies like those that established the benefits of injectable GLP-1 RAs such as tirzepatide, semaglutide, dulaglutide, and liraglutide on CKD, MASH, and cardiovascular outcomes will be crucial in determining the full clinical utility of these novel agents