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Notably, their small size facilitates transport across the BBB via endocytosis, followed by biodegradation within the brain microenvironment, which results in the controlled release of the encapsulated drug [108]

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A2A receptor activation upregulates vascular endothelial growth factor (VEGF), promotes angiogenesis in dermal microvasculature, stimulates fibroblast migration and proliferation, and suppresses inflammatory cytokine release

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Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human GCK