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The peptide chelates free copper ions that could otherwise participate in pro-oxidant Fenton reactions, while simultaneously stimulating the expression of endogenous antioxidant enzymes such as superoxide dismutase, catalase, and glutathione peroxidase

It serves as a powerful tripeptide that detoxifies cells while regenerating Vitamin Cs antioxidant properties

Among antioxidant enzymes, our recent studies have shown evidence of impaired functioning of the enzyme paraoxonase 1 (PON1) associated to high-density lipoprotein (HDL) in individuals with AD, with reduced protein levels and enzyme activity (60, 61)

As we age, experience stress, and are exposed to toxins, their levels decline

Nicorandil/ morphine crosstalk accounts for antinociception and hepatoprotection in hepatic fibrosis in rats: Distinct roles of opioid/cGMP and NO/KATP pathways