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Most research protocols favor a strategy of smaller, more frequent doses (micro-dosing) during the initial loading phase

Researchers analyzed change in HbA1c, body weight, fasting plasma glucose and continuous glucose monitoring parameters from baseline to 32 weeks

Nevertheless, the mean age at death for individuals born between 1985 and 1999 has been 29 years, and earlier diagnosis by newborn screening, treatment with more palatable cystine-depleting agents, and trials with gene therapy are critical current pursuits

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Electrographic seizures are significantly reduced by in vivo inhibition of neuronal uptake of extracellular glutamine in rat hippocampus