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In published research protocols, BPC-157 has been studied across a dosing range of 1-10 mcg/kg in animal models, with the majority of positive results observed at doses between 2-10 mcg/kg administered intraperitoneally or subcutaneously

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Nonetheless, several microbiota-derived precursor molecules, such as tryptophan and its metabolite 5-hydroxytryptophan (5-HTP), which are precursors to serotonin, as well as tyrosine and levodopa (L-DOPA), which are precursors to dopamine, can cross the BBB and subsequently modulate CNS neurotransmitter availability [187]

Tissue preparation, staining and analysis Intestinal tissues were flushed with PBS and fixed as a Swiss roll in 10% buffered formalin overnight