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Effects of nitrogen addition on plant manganese nutrition in a temperate steppe

To improve quantitative robustness, the relative concentration of identified compounds was first normalized by the internal standard (d4-alanine, d5-phenylalanine, or d5-tryptophan) based on their correlation with metabolites in the QC samples (38)

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The estrogen-deficient state may disrupt this careful coordination of energy substrate uptake and utilization, impairing postprandial insulin-mediated suppression of adipose tissue lipolysis and leading to a chronic excess supply of circulating NEFA to the liver, eventually overwhelming its capacity for lipid removal to cause liver fat accumulation (86)