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Studies have shown that the Really Interesting New Gene E3 ubiquitin ligase inducible degrader of the LDL receptor (IDOL, also known as Myosin Regulatory Light Chain Interacting Protein, MYLIP) and PCSK9 promote the induced degradation of LDLR, thereby inhibiting cholesterol uptake [46]

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Several miRNA including miR-28 and miR-144 are integral to the activity and regulation of NRF2

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doi: 10.1111/jsr.12567