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4 Health CanadaLutrepulse (gonadorelin acetate) product monograph and storage guidance

Sterile water has no preservative, meaning reconstituted solutions should be used within 24 hours

Although these trials primarily enrolled individuals with relatively low DKD risk and were not designed to evaluate kidney outcomes specifically, exploratory analyses consistently indicated slower kidney disease progression across diverse eGFR and albuminuria levels [39-44]

Discontinuation was defined as lapse in GLP-1RA or BI prescription longer than 12 months

That reliability matters enormously for treatment planning and patient expectations