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The hormone PT-141 stimulates the release of the neurotransmitter dopamine, which is associated with sexual function

The age-related drop in NAD+ levels is caused by rising levels of CD38, a membrane-bound NADase that degrades both NAD+ and its precursor nicotinamide mononucleotide, according to a 2016 study in mice, which exhibit age-related declines in NAD+ levels similar to those seen in humans (7)

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This targeted signaling is what makes it particularly interesting in performance and recovery contexts, as it may support muscle adaptation and repair without the same systemic effects associated with traditional growth hormone or IGF-1 therapies