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After 5-FU treatment, PBS washing was performed once, and 100 l of fresh RPMI 1640 medium was added

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21 If you have reduced HNMT activity, you're more likely to accumulate intracellular histamine, which means even if your DAO is working fine in the gut, you may still have problems clearing histamine in your brain (contributing to brain fog, nervousness, sleep issues) and airways (contributing to respiratory symptoms)