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Building on this historical and technological context, the present section shifts focus from how these systems are developed to why they matter in practice, by dissecting the core functional roles that underpin their value in nutraceutical applications

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p = 0.008), but no statistically significant difference for CV mortality when PIONEER 6 was omitted

Alexandra J Sinclair, University of Birmingham, Institute of Metabolism and Systems Research, Birmingham, B15 2TT, UK