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26 Factors Affecting Intranasal Drug Delivery Effective intranasal drug delivery requires a comprehensive understanding of the anatomy of the nasal cavity and the intranasal drug delivery pathways in the brain

Targeting the p53-FOXO4 Axis: In senescent cells, the protein FOXO4 binds to p53 and sequesters it in the nucleus, preventing p53 from triggering cell death

Non-stimulatory and generally very well tolerated

Well, heres your chance to find out

Within the complex, p53 TAD2 residues 47 to 54 displayed increased rigidity upon binding and consistently maintain an -helical conformation throughout the MD calculations (Fig