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When evaluating phase I metabolism, it is important to look at the ratios of 2OH/4OH and 2OH/16OH to see which pathways are metabolically preferred

Neutrophils are the most abundant granulocyte in circulation (40%70% of blood leukocytes) and are often the first line of host defense, inhibiting or eliminating invading pathogens through the generation of cytokines, ROS, neutrophil extracellular traps, and other factors

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doi:10.1016/s0952-7915(99)80010-7