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10.4103/jewd.jewd_46_23 182
Glutathione IV Therapy Popular in India, this intravenous treatment works systemically to reduce melanin production
Nakayama T, Church DF, Pryor WA: Quantitative analysis of the hydrogen peroxide formed in aqueous cigarette tar extracts
Gpxs exist in multiple isoforms, with different cellular localization and different substrate specificity ( 2 O 2 , Prxs seem to be more active, given their higher intracellular concentration and rate constant ( GSH, exploiting the redox-active thiol residue (-SH) of cysteine, exerts its antioxidant function mainly via Gpxs-mediated reactions, which result in peroxide buffering with simultaneous oxidation of GSH to GSSG ( Besides the neutralization of free radicals produced in phase 1 liver metabolism of chemical toxins, GSH also participates in the protection from the resulting electrophilic substrates through the intervention of glutathione-S-transferases (GSTs)
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