Nevertheless, the literature reviewed herein points toward the need of more molecular-genetic studies in order to get more insights into synthesis pathways, metal-specificity, and biological and non-biological factors responsible for the induction/expression of, and potential coordination among mechanisms underlying thiol- and non-thiol compounds-assisted metal-chelation
Diagnosis is made by measuring the concentration of different metabolites in the gamma-glutamyl cycle, enzyme activity and in glutathione synthetase and gamma-glutamylcysteine synthetase deficiency, also by mutation analysis
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Tasks go unfinished, switching between domains becomes extraordinarily hard, and the person may struggle to re-engage once pulled away from their focus tunnel