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A recent meta-analysis, including over 300,000 patients with T2DM worldwide, of whom over 50,000 subjects had PAD, examined whether SGLT2 inhibitors increase the risk of LLA compared to other glucose-lowering therapies

This prohibition extends to all sports and organizations that have adopted the World Anti-Doping Code, including the International Olympic Committee, national anti-doping agencies, and most professional and collegiate athletic organizations

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Medication interactions should be assessed before study enrollment