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Moreover, while GLP-1 analogs were originally designed for glycemic control in diabetic patients and subsequently applied to obesity, their utility has expanded into other metabolic conditions like NASH (fatty liver), and even cardiovascular disease prevention

The shorter half-life also means the end-of-week trough is more pronounced with tirzepatide

Lab review before starting: A baseline IGF-1, fasting glucose, and (where indicated) a thyroid panel sets the framework for response tracking

Medically reviewed by Dr Sultan Linjawi, Endocrinologist & Diabetes Specialist January 2026 What is Ozempic (Semaglutide)

Saxenda, Enobosarm, VK2735, TERN-601, and ECC5004, among others GLP-1 agonists are a type of medication used primarily in the treatment of type 2 diabetes and sometimes for weight management