AOD9604 and Safety Pharmacology Research A conventional Ames test showed no significant mutation rate increase for AOD9604 at up to 2,000 g/plate, with no clastogenic effects observed in CHO-cell chromosome aberration assays
Beyond individual trials, a 2025 meta-analysis covering over 140,000 participants found tirzepatide yields a mean 4.23% greater weight loss than semaglutide (95% CI: 3.22 5.25
Key publications: 'Tripeptide in human serum which prolongs survival of normal liver cells' (1973), 'Growth-modulating plasma tripeptide may function by facilitating copper uptake into cells' (1980, Nature), 'The human tri-peptide GHK and tissue remodeling' (2008), 'GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration' (2015), 'Regenerative and Protective Actions of the GHK-Cu Peptide' (2018)
It's more evidence for what I write about in "Lies I Taught in Medical School": the metabolic dysfunction driving obesity is the same dysfunction driving depression, anxiety, and addiction
J.SiderisS.KosakaY.et al (2019)