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In SCC25 human oral squamous carcinoma cells, cell viability decreased in a dose and timedependent manner after 24hr treatment with bromelain, from 95.16% (at 0.78 g/mL) to 69.93% (at 25 g/mL) (85)

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For the chin, we lean towards the longer end, because the submental area is small and visible, and rushing the spacing makes it harder to see what one session has actually achieved

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