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Large-scale clinical trials, including the SELECT cardiovascular outcome trial with over 17,000 participants, have not demonstrated increased overall cancer incidence with these medications compared to placebo groups
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For individuals with diabetes, the ketogenic diet in combination with GLP-1 therapy could increase the risk of diabetic ketoacidosis and hypoglycemia
Flushing: The copper component of GHK-Cu occasionally causes temporary skin flushing
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