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Ice age animals include extinct species such as mammoths, woolly rhinoceroses, and cave bears (whose related gene sequence information is obtained through ancient DNA technology), as well as existing animals adapted to cold environments such as polar bears and reindeer

One interesting possibility is that -glutamyl can be complexed to extracellular available free cyst(e)ine, imported into the cell and as such can serve as a substrate for GS during GSH synthesis (bypassing GCL reaction)

Glutathione is a tripeptide that is synthesized by forming one peptide bond between the gamma-carboxyl group of glutamate and the amino group of cysteine (forming gamma- glutamyl cysteine), and then by forming a second peptide bond between the carboxyl group of cysteine and the amino group of glycine

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Cutaneous fungal infections in eczema: Diagnosis and treatment considerations