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In contrast, the cytotoxicity in the PDA@Pt + Laser (808 nm, 1 W/cm 2 ) group was decreased, with cell viability reaching 94.7% at a concentration of 40 g/mL and dropping below 80% at 50 g/mL (Fig

The two are inextricably linked through a biological pathway known as the GH/IGF-1 axis

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This distribution pattern means AOD-9604 exerts its strongest effects precisely where intended with minimal off-target effects on other organ systems

Moreover, the dose- and size-dependent cytotoxicity observed suggests that GO can effectively target and neutralize bacterial cells by compromising essential organelle-like structures and functions