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It seems to work in waves
Subsequent studies demonstrated that apelin signaling is highly context dependent, with differential coupling to G_i, G_q, and -arrestin pathways depending on ligand structure, receptor density, and tissue environment ( Translationally, the apelinAPJ system illustrates a broader challenge for metabolic peptides with cardiovascular overlap: indication-specific development is likely required
Sulieman S, Schulze J (2010) Phloem-derived gammaaminobutyric acid (GABA) is involved in upregulating nodule N2 fixation efficiency in the model legume Medicago truncatula
Stable Gastric Pentadecapeptide BPC 157: Novel Therapy in Gastrointestinal Tract
Mediterranean diet and health status: an updated meta-analysis and a proposal for a literature-based adherence score
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