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TP53 regulates several key metabolic and apoptotic pathways, including the expression of cytochrome c oxidase 2 (SCO2) and glutaminase 2 (GLS2) [85], TP53 upregulated modulator of apoptosis (PUMA) [86], and the glucose transporters GLUT1 and GLUT4 [87]

Itoh K, Wakabayashi N, Katoh Y, Ishii T, OConnor T, Yamamoto M

To further determine if the early changes in peptide/protein abundance are related to the change in C-peptide in the longer term, the trends in peptide levels during the first year were compared with the fasting C-peptide/glucose ratios at 24 months

Hair loss is so common that a B12 deficiency as the cause of it is often missed

Based on its mechanism (synaptogenesis and HGF/c-Met pathway activation), Dihexa research is theoretically most relevant to: (1) Age-related cognitive decline (synaptic loss is a hallmark of brain aging)