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Cagrilintide is a long-acting amylin analogue administered once weekly by subcutaneous injection, reducing appetite by slowing gastric emptying and suppressing glucagon

While peptides are generally less immunogenic than larger proteins, they can still trigger antibody formation in some patients

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all the SNPs had F-statistics above 10

The point estimate of the ratio (ESRD group/normal renal function group) for AUC 48 (without hemodialysis) was 0.72 (90% CI 0.570.91) and for AUC 4896 (with hemodialysis) was 0.82 (90% CI 0.670.99)