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Although both forms have been shown to improve endurance, reduce muscle soreness, and support fat loss, their effects may vary depending on individual health goals

A1298C Variant (rs1801131): While this variant has a smaller impact on homocysteine levels, it has been associated with neurotransmitter imbalances, mood disorders, and chronic fatigue [5]

Stress exacerbates fatigue, so calming the mind counts

doi: 10.1097/XCS.0000000000000325

GW: Well, it was interesting in the book that you got access to all the coolest researchers that were running an immune panel on you to say, "Oh, yeah, Eric Topol has had rhinovirus 15 times, and you've had coxsackie-2 three times or whatever." It was interesting that those markers are stuck in your body permanently, that those can be detected, clearly opened the door to this idea that these viruses are making their impact on us and leaving their footprints permanently