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( BE ) Plasma DPP-4 activity before (time 30 minutes) and 90 minutes after oral gavage of water or sitagliptin as indicated ( B , n = 914/group), plasma TG and AUC over 3 hours ( C , n = 914/group), and apoB48 and apoB100 protein levels measured by Western blot (WB) ( D and E , n = 35/group) after oral gavage of water or sitagliptin, followed by i.v

These cumulative costs rival or exceed metabolic surgery for obesity, which provides permanent anatomical changes without ongoing medication costs

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Hunot S, Brugg B, Ricard D, Michel PP, Muriel MP, Ruberg M, et al