Myasoedova VA, Bozzi M, Valerio V, Moschetta D, Massaiu I, Rusconi V, Di Napoli D, Ciccarelli M, Parisi V, Agostoni P et al
If you miss a dose, follow product-specific instructions: For Ozempic, if more than 5 days have passed, skip that dose and take the next dose on the regularly scheduled day
Insulin sensitivity appears not to be directly affected by GLP-1RAs
Skipping this careful titration process through microdosing can prevent patients from reaching the therapeutic levels needed for effective treatment
However, adjustments may be considered if: Glycaemic targets are not achieved : Your doctor may increase to the next available dose strength Intolerable side effects persist : A temporary dose reduction or slower titration may be appropriate Weight loss plateaus (for weight management indications): Dose optimisation may be discussed Renal function changes : Monitoring may be increased, though most GLP-1s don't require dose adjustment Other medications are added or removed : Particularly other glucose-lowering agents Important considerations during dose changes: Never skip doses or double up if you miss an injectionfollow the specific guidance in your patient information leaflet For missed doses, each product has different instructions: Semaglutide (Ozempic/Wegovy): If within 5 days, take as soon as possible