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Body comp matters more than scale weight for real Stephanie L., 33, Kelowna BC Resistance Training Lifting weights 2-3x weekly during treatment preserves muscle that would otherwise be lost during rapid weight reduction

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In a January 2026 analysis, the most-engaged Noom GLP-1 Rx Program membersthose who use the Noom app most frequentlylost 25.2% more weight, on average, by week 40, than the least-engaged members (comparing the top and bottom quartiles based on engagement)

These include caffeine, stimulants (such as amphetamines for ADHD), wakefulness agents, oral nasal decongestants, asthma medications (bronchodilators), corticosteroids, sympathomimetics, and weight loss medications

The logic behind combining these compounds becomes clear when considering the challenge of significant weight loss