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Medical Condition Adjustments: The Sixth Key Guideline Adjusting B12 doses is key for people with health issues that affect how nutrients are absorbed

Many patients come to us concerned about persistent tiredness, weakness, or fatigue that interferes with their daily life

Fortunately, such reactions are extremely infrequent

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Neurological symptoms represent a significant concern with B12 deficiency and may include: Paraesthesia (pins and needles) in the hands and feet Difficulty with balance and coordination Memory problems or cognitive changes Mood disturbances , including depression or irritability Glossitis (sore, red tongue) and mouth ulcers Haematological manifestations of B12 deficiency include megaloblastic anaemia , characterised by the production of abnormally large, immature red blood cells