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After initial repletion, a maintenance dose is given, often 1,000 mcg intramuscularly every month or every 2 to 3 months, to prevent recurrence of deficiency

Front Cell Infect Microbiol 11:755925 Asher S (2022) Periodontal health, cognitive decline, and dementia: a systematic review and meta-analysis of longitudinal studies

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Expected timeline: Month 1-2: Inflammation management, symptomatic improvement Month 3-6: Potential slowing of degenerative markers, quality of life improvement Month 6-12: Assessment of structural changes, protocol optimization Ongoing: Maintenance protocols as needed, cycling strategies Complementary approaches: Anti-inflammatory nutrition

lo que genera un ahorro de glucgeno muy importante, principalmente en momentos de intensa actividad, generando un aporte de energa, as como mayor resistencia, disminuyendo el dolor y cansancio muscular