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This concentration often hits a sweet spot

In another study, rats were used as a model of tardive dyskinesia, a disorder characterized by involuntary neurological triggering that leads to spontaneous, repetitive body movements, such as grimacing, sticking out the tongue, or lip movements that were simulated by injection of reserpine

This stability may explain why relatively low doses produce noticeable effects

Myeloid LXR (Liver X Receptor) Deficiency Induces Inflammatory Gene Expression in Foamy Macrophages and Accelerates Atherosclerosis

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