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The column was subjected to gradient program by using Mobile Phase A: Water and Mobile Phase B: Acetonitrile

Formononetin ameliorates ferroptosis-associated fibrosis in renal tubular epithelial cells and in mice with chronic kidney disease by suppressing the Smad3/ATF3/SLC7A11 signaling

The main contributing factors include: A low-fiber diet Fiber helps bulk stool, preventing constipation and reducing pressure on the colon