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Furthermore, as with the use of the combination of anti-CTLA-4 and anti-PD-1 or anti-PD-L1, the frequency and severity of irAEs were higher than with single immune checkpoint inhibitor monoclonal antibody treatment

Whether the clinical benefit was confined to EPA only or it can be generalized to all omega-3 PUFA is still yet to be determined

But clinical trial averages don't predict your personal outcome, and results from FDA-approved formulations in controlled trials don't certify identical performance from a compounded formulation