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CrossRef The mitochondrial unfolded protein response and mitohormesis: a perspective on metabolic diseases Hyon-Seung Yi, Joon Young Chang, Minho Shong Journal of Molecular Endocrinology.2018

Among the commonly upregulated genes in 3D samples, we identified three genes which could contribute to ferroptosis protection, namely Sepw1, Muc1, and Ggt1

While some ROS act as signaling molecules under physiological conditions, excess production disrupts redox homeostasis and damages proteins, lipids, and DNA ( Mitochondria are the primary source of intracellular ROS, primarily generated during electron transfer through complexes I-IV of the electron transport chain (ETC) (Michaelson et al., 2013)

Puncturevine ( Tribulus terrestris L.) affects the proliferation, apoptosis, and ghrelin response of ovarian cells