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BPC-157 completely eliminated autotomy behavior, suggesting direct effects on neuropathic pain reduction alongside structural nerve repair

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(US Patent 8598118) characterized hepatocyte growth factor mimics as therapeutic agents and established the mechanistic basis for Dihexas development

A group from California Institute of Technology (Caltech) has utilized a multivalent engineered protein domain called SpyCatcher to fuse antigens to virus-like particles

A 2016 review by Sikiric and colleagues in Current Neuropharmacology framed BPC-157's effects within a brain-gut axis model, while a 2024 review by Sikiric and colleagues in Pharmaceuticals (Basel) examined the peptide's relationships with multiple neurotransmitter systems