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Researchers believed Semaglutide could potentially help with PAD through: Anti-inflammatory Effects: As mentioned, inflammation is a key driver of atherosclerosis

The hormone stimulates glucose-dependent insulin secretion from pancreatic beta cells, meaning insulin release occurs only when blood glucose levels are elevated

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Some clinicians are exploring the use of SGLT2 inhibitors alongside GLP-1 or dual GIP/GLP-1 receptor agonists to maximize metabolic outcomes

Bile acids help break down fats and carry fat-soluble vitamins