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Byvetta, the first to be approved, faced lawsuits and gained a FDA warning after being associated with several severe cases of pancreatitis

Allen RW, Schwartzman E, Baker WL, Coleman CI, Phung OJ

In summary, recent CV outcomes trials with GLP-1RAs have shown promising benefits in CV care of T2D patients, and GLP-1RAs have been accordingly listed as a second line therapy in T2D patients with established atherosclerotic CV disease, alongside SGLT2 inhibitors [5, 6]

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