this deficit may be pathoplastic and influence the treatment outcomes [e.g., treatment resistance ( In addition to the above considerations, it is also likely that the use of antipsychotics and other medications as well as a high degree of variability in lifestyle factors and daily functioning (including diet) may make the patient group more heterogenous
Exploratory endpoints included achieving 15% and 20% weight loss, and patient-reported outcomes assessed using the SF-36 v2.0 and the Three-Factor Eating Questionnaire (TFEQ-R18 v2)
Semaglutide medications like Ozempic have transformed weight loss treatment, but gastrointestinal side effects affect up to 50% of users during initial dosing phases
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"There are some [people] that, despite doing all of this, might have difficulty losing weight, and for those, I recommend talking to a provider to review the variety of medications and interventions that might help."