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& Premont, J

Nonetheless, I figured Id mention them

Tendon tissue is poorly vascularised and heals slowly, so an angiogenic compound draws particular interest here

So they may lose weight initially, but then they plateau, feel worse, or regain the weight when they stop." Another issue is that GLP-1 medications can cause muscle loss and a drop in metabolic rate, which may make long-term weight maintenance more difficult

Under pathological conditions, they may initially exert neuroprotective effects, yet prolonged activation often results in metabolic disturbances and neurotoxic gliotransmission, highlighting their dual role in CNS pathology and their potential in therapy [293]